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How to Recognize and Address Codeine Addiction
Every week, thousands of Canadians pick up codeine prescriptions from their local pharmacy. A routine dental procedure. Post-surgery pain management. The doctor hands over pills - maybe Tylenol #3 or cough syrup. "Take as needed," they say. Most patients follow directions. But for some, those tablets become something dangerous. The medicine that was supposed to help starts controlling their life.

Key Takeaways
- Addiction happens fast - Physical dependence develops after just 10-14 days of regular use
- Small changes add up - Running out early, extra doses, asking for refills ahead of schedule
- Withdrawal is brutal - Flu-like symptoms, depression, insomnia that last weeks
- Treatment works - Medical supervision prevents complications and improves success rates
- Getting help early matters - Catching problems before they spiral saves relationships and lives
What Is Codeine and Why Does It Become Addictive?
Codeine comes from opium poppies - the same plant that produces heroin and morphine. When you swallow a codeine pill, your liver converts about 10% into morphine, which kills pain and creates euphoria. Some people's bodies are efficient at this conversion and get morphine-level effects from mild painkillers.
Your brain doesn't care where morphine comes from. Pain disappears. Stress melts away. Your brain starts expecting that feeling. When it doesn't come, you feel awful.
Pills work less over time. What knocked out pain for six hours barely lasts three. You take them closer together. Then two instead of one. Before you realize it, you're planning your day around your next dose.
Common codeine medications include:
- Tylenol #1, #2, #3, and #4 (increasing codeine amounts)
- 222’s from gas stations and corner stores
- Prescription cough syrups like ratio-Cotridin
Combination products are tricky. Someone taking six Tylenol #3s gets the buzz they want but also 1,800mg of acetaminophen - enough to damage their liver.
What Are the Early Warning Signs of Codeine Addiction?
Sarah noticed her prescription running out faster than it should. She'd count pills and do the math - there should be more left. But there wasn’t. She told herself she must have miscounted at the pharmacy.
That's how it starts. Not with dramatic changes. Just small things that don't make sense.
Pills disappear quicker than expected. Refill requests come early with explanations - "I'm going out of town" or "I dropped some." Different pharmacies are used in order to avoid lectures about early refills.
Physical changes happen gradually. Constant tiredness after a full sleep. Pupils that remain constricted in dark rooms. Bowel movements maybe once weekly. Balance gets worse. Speech becomes unclear.
Watch for these behaviors:
- Taking pills ahead of schedule consistently
- Crushing tablets for stronger effects
- Visiting multiple doctors with pain complaints
- Buying medication from street dealers
- Panicking when supplies run low
The lies start small: "I lost some pills" or "The doctor said I could take more." By the time family asks direct questions, the person has usually been taking more than prescribed for months.
How Long Does Codeine Stay in Your System?
Codeine shows up in urine for 1-3 days after your last dose. Regular users might test positive for a week. Blood tests catch it for 24 hours. Saliva tests work for 1-4 days.
Your timeline depends on factors you can't control. Age makes a huge difference: a 70-year-old processes codeine much slower than a 25-year-old. Liver problems slow elimination. Dehydration keeps everything in your system longer.
Some people have genetic variations affecting codeine breakdown. About 7% of caucasians are "poor metabolizers" - their bodies can't convert codeine to morphine well. These people might not get pain relief from normal doses and the codeine hangs around longer.

What Are the Most Common Codeine Side Effects?
Codeine side effects hit everyone differently, but some patterns emerge quickly. Drowsiness arrives first and hardest. New users feel like they're walking through fog. Driving becomes dangerous. Work concentration disappears.
Constipation affects nearly everyone taking codeine regularly. We're talking about not having bowel movements for days or weeks. Many people end up in emergency rooms with impacted bowels.
Nausea comes unpredictably. Sometimes empty stomaches trigger vomiting. Other times, eating first makes nausea worse.
Regular codeine side effects include:
- Mouth so dry talking becomes difficult
- Zero appetite leading to weight loss
- Itching all over with no visible cause
- Trouble urinating with a full bladder
Dangerous codeine side effects happen with too much medication. Breathing slows to 4-6 breaths per minute instead of the normal 12-16. Lips can turn blue. The heart rate drops. The person might be conscious but unable to respond.
Tylenol #3 contains 300mg acetaminophen per tablet. Someone taking 8-10 pills daily gets 2,400-3,000mg - approaching levels that cause liver damage.
What Does Codeine Withdrawal Feel Like?
Mike had been taking 8-10 Tylenol #3’s daily for six months when he quit cold turkey. By hour 12, he realized he was in trouble.
Codeine withdrawal starts with restlessness. He couldn't sit still or get comfortable. Sleep became impossible despite exhaustion. By day two, every muscle ached like he'd run a marathon. His nose wouldn't stop running.
Stomach cramps doubled him over. Diarrhea alternated with nausea that made eating impossible. He'd shiver under blankets, then sweat through clothes within minutes.
The depression hit him like a black cloud. Everything seemed hopeless. Getting out of bed required tremendous effort.
Physical codeine withdrawal symptoms peak around day 3-4, then slowly improve over the following week. But mental symptoms drag on for months. Depression lifts for days, then crashes back. This is why many people relapse during codeine withdrawal.
What Codeine Addiction Treatment Options Are Available?
Trying to quit alone rarely works. Withdrawal is too uncomfortable, cravings too strong, depression too overwhelming. Professional codeine addiction treatment makes success more likely.
Medical detox provides comfortable withdrawal management. Doctors prescribe medications reducing specific symptoms. Nurses monitor vital signs. Mental health counselors provide support when depression hits.
Tapering works for motivated patients. Instead of stopping completely, doses are reduced gradually over weeks. This minimizes withdrawal but requires strict adherence to reduction schedules.
Counseling addresses why addiction developed. Individual therapy identifies triggers and develops coping strategies. Group sessions connect people with others who understand. Family therapy repairs damaged relationships.
Outpatient codeine addiction treatment programs let people maintain responsibilities while getting help. Residential treatment makes sense for severe addictions or multiple failed attempts.

When Should You Seek Professional Help?
Get help if you're taking codeine more often or in higher doses than prescribed. Get help if you're visiting multiple doctors for more pills. Get help if running out causes panic.
Get help if family members express concern about pill usage. Get help if you've lied about amounts or hidden pills. Get help if you've tried stopping alone and couldn't.
The Canadian Centre for Addictions has extensive experience treating prescription opioid addiction. Our medical team provides individualized treatment plans with both inpatient and outpatient options.
Don't wait for things to get worse. Call today for a confidential assessment and learn about treatment options that can help you reclaim your life from codeine addiction.
FAQ
How quickly can someone become addicted to codeine?
Physical dependence can happen within 10-14 days of regular daily use, even at prescribed doses.
Can you overdose on over-the-counter codeine products?
Yes, products like 222 tablets contain real codeine and can cause overdoses, especially when taken with alcohol.
What's the difference between codeine dependence and addiction?
Dependence means physical withdrawal when stopping, while addiction means continued use despite consequences.
Are there alternatives to codeine for pain management?
Many alternatives exist including ibuprofen, topical pain relievers, physical therapy, and non-opioid prescriptions.
How long does codeine addiction treatment typically take?
Medical detox lasts 5-10 days, but ongoing therapy often continues for months to maintain recovery.